House holiday rentals in Panama
Find and book unique houses on Airbnb
Top-rated house rentals in Panama
Guests agree: These houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama house rentals
House rentals with a pool
Home in Rio Hato
4.77 out of 5 average rating, 90 reviewsBeautiful Villa with Big Pool of 50m2
Home in Panama City
4.94 out of 5 average rating, 31 reviewsCheerful Casa Duplex with swimming pool.
Home in Bocas Del Toro
4.96 out of 5 average rating, 101 reviewsWiona of Villa Paraiso | Beachfront Villa & Pool
Home in David
4.69 out of 5 average rating, 36 reviewsCasa Piscina - House with a pool in David
Home in Nueva Gorgona
4.88 out of 5 average rating, 43 reviewsLarge private house pooled house (Late check-out)
Home in Río Hato
4.86 out of 5 average rating, 84 reviewsPoolside Paradise in Santa Clara
Home in Las Lajas
4.88 out of 5 average rating, 40 reviewsRelax and Unwind at Las Lajas Beach House
Home in El Chirú
4.94 out of 5 average rating, 16 reviewsSecluded House | Saltwater Pool | Near Beaches
Weekly house rentals
Home in Nueva Gorgona
4.93 out of 5 average rating, 14 reviewsSpectacular property with beach access
Home in Bocas del Toro
5 out of 5 average rating, 12 reviewsSurf Shangri-la in Bluff Beach
Home in Las Lajas
4.88 out of 5 average rating, 8 reviewsPerfect Getaway Mountain like House with pool
Home in La Chorrera
4.71 out of 5 average rating, 17 reviewsCozy and Comfy House. Quiet and safe
Home in Playa Venao
4.94 out of 5 average rating, 18 reviewsNext to Beach Club: Blue 2 Bedroom Family Villa
Home in Boquete District
5 out of 5 average rating, 20 reviewsFamilyHome Casa Tropical
Home in Playa Hermosa
5 out of 5 average rating, 28 reviewsEntire house with private pool facing beach !
Home in Nueva Gorgona
4.85 out of 5 average rating, 41 reviewsComfortable beach house, mall search, weekly discounts
Private house rentals
Home in Playa Venao
4.83 out of 5 average rating, 12 reviewsModern Beach Home with pool and hot tub
Home in Las Lajas
4.93 out of 5 average rating, 15 reviewsCozy and beautiful house in Las Lajas, Chame
Home in Colón
4.83 out of 5 average rating, 40 reviewsFamily style living and close to the Panama Canal
Home in El Chirú
4.81 out of 5 average rating, 54 reviewsMimi’s Beach House in Rio Hato
Home in Bocas del Toro Province
4.91 out of 5 average rating, 86 reviewsCasita Chalet Tropical with Swimmingpool
Home in Boquete
5 out of 5 average rating, 19 reviewsCasa Camila Apartment
Home in Playa Coronado
5 out of 5 average rating, 10 reviewsSpacious Home with Lovely Pool, 2bdrm
Home in Anton Valley
5 out of 5 average rating, 37 reviewsBeautiful Country House
Destinations to explore
- Farmstay rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Rentals with pools Panama
- Loft rentals Panama
- Pet-friendly rentals Panama
- Boutique hotel rentals Panama
- Rentals with beach access Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Island rentals Panama
- Rentals with a home theatre Panama
- Rentals with lake access Panama
- Waterfront rentals Panama
- Rentals with a patio Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Condo rentals Panama
- Villa rentals Panama
- Monthly Rentals Panama
- Fitness-friendly rentals Panama
- Chalet rentals Panama
- Tree house rentals Panama
- Cottage rentals Panama
- Townhouse rentals Panama
- Rentals with an accessible height bed Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Kid-friendly rentals Panama
- Family-friendly rentals Panama
- Tiny house rentals Panama
- Rentals with a hot tub Panama
- Rentals with a sauna Panama
- Nature eco lodge rentals Panama
- Bed and breakfasts Panama
- Rentals with breakfast Panama
- Smoking-friendly rentals Panama
- Boat rentals Panama
- Beach house rentals Panama
- Apartment rentals Panama
- Rentals with a fireplace Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Rentals with a fire pit Panama
- Guesthouse rentals Panama
- Rentals with a washing machine and dryer Panama
- Hotel rentals Panama
- Bungalow rentals Panama
- Beach condo rentals Panama
- House rentals Panama City
- Guesthouse rentals Panama City
- House rentals Playa Coronado
- House rentals Altos del Maria
- Yurt Rentals United States
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- Houseboats United States
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- Luxury Dog-Friendly Cottages United Kingdom