Guesthouse holiday rentals in San Diego
Find and book unique guesthouse rentals on Airbnb
Top-rated Guesthouses in San Diego
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for San Diego guesthouses
Family-Friendly guesthouses
Guesthouse in Chula Vista
4.95 out of 5 average rating, 476 reviewsPrivate Casita in Great Eastlake Neighborhood
Guesthouse in San Diego
4.97 out of 5 average rating, 509 reviewsCentral & Serene Secret Garden Guesthouse
Guesthouse in San Diego
4.97 out of 5 average rating, 294 reviewsPrivate Guest House with a View
Guesthouse in Oceanside
4.92 out of 5 average rating, 266 reviewsThe Sunshine House. Location, Location, Ocean.
Guesthouse in San Diego
4.95 out of 5 average rating, 478 reviewsRomantic Private Garden Studio Near Downtown
Guesthouse in San Diego
4.89 out of 5 average rating, 111 reviewsSoCal Tiny Home, Heart of South Park
Guesthouse in La Mesa
4.92 out of 5 average rating, 208 reviewsFig Tree Bungalow
Guesthouse in El Cajon
4.98 out of 5 average rating, 191 reviewsFletcher Hills - modern 1 BR.Easy, no step access.
Guesthouses with a patio
Guesthouse in San Diego
5.0 out of 5 average rating, 110 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
Guesthouse in Lakeside
4.94 out of 5 average rating, 103 reviewsSky Mesa-Adorable Cottage on the Hill
Guesthouse in San Diego
4.99 out of 5 average rating, 152 reviewsAdorable cottage in Talmadge
Guesthouse in La Mesa
4.98 out of 5 average rating, 252 reviewsLa Mesa Suite
Guesthouse in Spring Valley
4.97 out of 5 average rating, 114 reviewsLoft Cabin-Night Cinema+Hot Soaking Tub+Views!
Guesthouse in San Diego
4.98 out of 5 average rating, 127 reviewsPrivate Studio Cottage with Outdoor Patio
Guesthouse in San Diego
4.98 out of 5 average rating, 101 reviewsKing Bed, Free Parking, Fast Wi-Fi, Full Kitchen
Guesthouse in National City
4.9 out of 5 average rating, 100 reviewsPrivate Studio ONLY 4 Miles to SD Gaslamp Quarter!
Guest house rentals with a washing machine and dryer
Guesthouse in San Diego
4.93 out of 5 average rating, 148 reviewsPoint Loma Private Apartment
Guesthouse in San Diego
4.87 out of 5 average rating, 420 reviewsThe Golden Hill mosaic "casita"
Guesthouse in San Diego
4.95 out of 5 average rating, 213 reviewsPrivate beach guesthouse w/ private parking
Guesthouse in San Diego
4.94 out of 5 average rating, 105 reviewsAdorable studio/self check-in & off street parking
Guesthouse in San Diego
4.96 out of 5 average rating, 116 reviews1BR Casita in the Heart of Kensington!
Guesthouse in San Diego
4.92 out of 5 average rating, 508 reviewsQuaint Craftsman#2- Walkable, Parking, EV Charging
Guesthouse in San Diego
4.92 out of 5 average rating, 529 reviewsThe Best Cottage in North Park!
Guesthouse in San Diego
4.97 out of 5 average rating, 307 reviewsPrivate Guesthouse in Trendy North Park
Quick stats about guesthouse rentals in San Diego
Total rentals
980 properties
Rentals with dedicated workspaces
530 properties have a dedicated workspace
Rentals with a pool
90 properties have a pool
Pet-friendly rentals
240 properties allow pets
Family-friendly rentals
140 properties are a good fit for families
Total number of reviews
101K reviews
Destinations to explore
- Tijuana Holiday rentals
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